Crew transport (normally you have to add a spaceship for this, but Shuttle already is one).And what mission can conduct Shuttle that conventional single use rockets cannot?
Large-capacity space station logistics, both pressurized and unpressurized (normally you have to add a spaceship for this, but Shuttle already is one). Bonus: you get a crew surge to help with unloading and anything else that needs doing.
EVA and RMS functionality (space construction and repair).
Hauling stuff around on orbit (space tug), or dealing with multiple satellites on one mission (yes, it's been done).
Low-gee-loading rapid-access downmass, both pressurized and unpressurized. Lots of it.
Mini space station capability (crew on orbit in free flight for up to a week and a half, or longer with extra equipment added, including potential hab space in the payload bay).
...
There's a market for Shuttle-class capability. Turns out it was just ahead of its time:
http://www.marylynnedittmar.com/?p=1303
http://www.nasaspaceflight.com/2011/12/ ... ters-ends/